Spiny-cheeked Honeyeaters are the common, large honeyeaters of the inland where they occupy the niche held in more coastal regions by the wattlebirds. Once adult, they live as pairs in permanent territories although they may congregate in small flocks at rich food sources in dry times. They feed largely on small fruits and berries and arthropods but nectar is also eaten when available.

Their musical piping calls are a common early morning sound in the inland. Males also fly vertically in a short display flight to advertise territory ownership.